Publication / 2019

  • T. Nakanishi, K. Yamagishi, E. Iwase, H. Iwata, S. Takeoka, T. Fujie
  • Applied Physics Express, 12, 075001 (2019)

  • Jieyan He, Tianshu Li, Tomasz Próchnicki,Gabor Horvath,Eicke Latz ,and Shinji Takeoka
  • Biochem Biophys Rep., 2019 Jul; 18: 100623.

  • Li T, Zehner M, He J, Próchnicki T, Horvath G, Latz E, Burgdorf S, Takeoka S
  • International Journal of Nanomedicine, 13 May 2019 Volume 2019:14 Pages 3503—3516

  • Arihiro Hasebe, Yoshitaka Suematsu, Shinji Takeoka, Tommaso Mazzocchi, Lorenzo Vannozzi, Leonardo Ricotti, and Toshinori Fujie
  • ACS Biomaterials Science & Engineering, DOI: 10.1021/acsbiomaterials.8b01550

  • K Ikeda, S Takeoka
  • Journal of Clinical Medicine and Therapeutics, 2018, Vol. 3, No. 1:4

  • K Yamagishi, S Takeoka, T Fujie
  • Biomaterials Science, 10.1039/c8bm01290c

  • N Kokubo, M Arake, K Yamgishi, Y Morimoto, S Takeoka, H Ohta, T Fujie
  • ACS APPLIED BIO MATERIALS, 2019, 2 (1), pp 20–26

  • H Kiuchi, S Takeoka
  • レギュラトリーサイエンス学会誌, 2018 年 8 巻 3 号 p. 143-149

  • K Nishiwaki, S Aoki, M Kinoshita, T Kiyosawa, Y Suematsu, S Takeoka, T Fujie
  • Society For Biomaterials, 10.1002/jbm.b.34228

  • K Yanagishi, I Kirino, I Takahashi, H Amano, S Takeoka, Y Morimoto, T Fujie
  • Nature Biomedical Engineering, 3, pages27–36 (2019)

  • S Sarker, S Takeoka
  • Journal of Nanomedicine,

  • T Li, S Takeoka
  • Smart Nanoparticles for Biomedicine, 2018, Pages 31-47

  • K Yamagishi, S Taccola, S Takeoka, T Fujie, V Mattoli, F Greco
  • Flexible and Stretchable Medical Devices, 10.1002/9783527804856.ch11

Publication / 2018

  • Someya, D., Arai, S., Takeoka, S., Fujie, T
  • RSC Adv, DOI: 10.1039/C8RA06308G

  • Nishiwaki, K., Aoki, S., Kinoshita, M., Kiyosawa, T., Suematsu, Y., Takeoka, S., Fujie, T
  • J. Biomed. Mater. Res. B, DOI: 10.1002/jbm.b.34228

  • Kento Yamagishi, Izumi Kirino, Isao Takahashi, Hizuru Amano, Shinji Takeoka, Yuji Morimoto, Toshinori Fujie
  • Nature Biomedical Engineering, DOI:1038/s41551-018-0261-7

  • Tianshu Li, Jieyan He, Gabor Horvath, Tomasz Prochnicki, Eicke Latz, Shinji Takeoka
  • Nanomedine: nanotechnology, biology and medicine, Volume14, 279-288(2018).

  • Kazuhiro Takahashi, Toshinori Fujie, Nobutaka Sato, Shinji Takeoka, Kazuaki Sawada
  • Japanese Journal of Applied Physics, 57(1), (2018)

[Review] Amino acid-based liposomal assemblies: Intracellular plasmid DNA delivery nanoparticles.

  • Sarker SR, Takeoka S.
  • J Nanomed. 2018; 2: 1008.

[Book] Chapt 3, "Smart liposomes for drug delivery", Smart Nanoparticles for Biomedicine, Ed.Gianni Ciofani

  • Tianshu Li and Shinji Takeoka
  • Book ISBN: 9780128141571, Elsevier, (2018)

[Book] Conductive Nanosheets for Ultra-Conformable Smart Electronics

  • Kento Yamagishi, Silvia Taccola, Shinji Takeoka, Toshinori Fujie, Virgilio Mattoli, Francesco Greco
  • pp253-285 Flexible and Strechable Medical Devices, Ed. Kuniharu Takei, Wiley-VCH (2018)

Publication / 2017

  • Komachi, T.a, Sumiyoshi, H.b, Inagaki, Y.b, Takeoka, S.c, Nagase, Y.a,
  • Journal of Biomedical Materials Research - Part B Applied Biomaterials, 105(7), 1747-1757(2017)

  • Sato, K., Noguchi, G., Asao, K., Murata, A.a, Fujie, T.cd, Nagase, Y., Takeoka, S.
  • Kobunshi Ronbunshu, 74(2), 99-108(2017)

  • Takahashi, K., Fujie, T., Sato, N., Takeoka, S., Sawada, K.
  • Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Article number 7863505, 704-707(2017)

  • Shimbo, S., Fujie, T., Iwase, E.
  • Proc. 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS), 624-627(2017)

  • Ricotti, L., Fujie, T.
  • Bioinspir. Biomim., 12, 021001(2017)

  • 藤枝 俊宣, 武岡 真司
  • 化学と工業, 70(6), 494-496(2017)

  • Agostina Grillone, Tianshu Li, Matteo Battaglini, Alice Scarpellini, Mirko Prato, Shinji Takeoka and Gianni Ciofani
  • Nanomaterials, 7(9), 276(2017).

  • Yuma Tetsu, Kento Yamagishi, Akira Kato, Yuya Matsumoto, Mariko Tsukune, Yo Kobayashi, Masakatsu G. Fujie, Shinji Takeoka and Toshinori Fujie
  • Applied Physics Express (APEX), 10, 087201(2017).

  • Kohei Kubota, Kohei Onishi, Kazuaki Sawaki, Tianshu Li, Kaoru Mitsuoka, Takaaki Sato, Shinji Takeoka
  • International Journal of Nanomedicine , 12, 5121-5133 (2017).

  • Silvia Taccola, Virginia Pensabene, Toshinori Fujie, Shinji Takeoka, Nicola M. Pugno, Virgilio Mattoli
  • Biomedical Microdevices, 19: 51(2017).

  • Eisuke Yamamoto, Kouya Nagata, Kenta Onishi, Chihiro Urata, Atsushi Shimojima, Hiroaki Wada, Shinji Takeoka, and Kazuyuki Kuroda
  • Bulletin of the Chemical Society of Japan , 90, 706–708(2017).

生体組織に調和する高分子ナノシートの医療・ヘルスケアへの展開

  • 藤枝 俊宣, 山岸 健人, 武岡 真司.
  • 化学工業, 67(2)

肌に貼り付けるだけで生体情報をモニタリングする電子ナノ絆創膏

  • 山岸 健人, 武岡 真司, 藤枝 俊宣.
  • Biophilia, 5(4)

生体適合性高分子ナノシートの物性と医療応用

  • 武岡 真司
  • 医療用バイオマテリアルの研究開発, シーエムシー出版

  • 佐藤 克典・野口  元・浅尾 幸平・村田  篤・藤枝 俊宣・長瀬  裕・武岡 真司
  • 高分子論文集, 74 (2), 99-108(2017).

Construction and evaluation of pH-sensitive immunoliposomes for enhanced delivery of anticancer drug to ErbB2 over-expressing breast cancer cells

  • Tianshu Li, Takuya Amari, Kentaro Semba, Tadashi Yamamoto and Shinji Takeoka
  • Nanomedicine: Nanotechnology, Biology, and Medicine, 13, 1219–1227 (2017)

Printed high-frequency RF identification antenna on ultrathin polymer film by simple production process for soft-surface adhesive device

  • Hayata, H., Okamoto, M., Takeoka, S., Iwase, E., Fujie, T., Iwata, H.
  • Jpn. J. Appl. Phys, 56, 05EC01 (2017)

Optomechanical characterization of freestanding stretchable nanosheet based on polystyrene-poly- butadiene-polystyrene copolymer

  • Hayato Kumagai, Nobutaka Sato, Shinji Takeoka, Kazuaki Sawada, Toshinori Fujie and Kazuhiro Takahashi
  • Applied Physics Express, 10, 11601 (2017)

Development of Flexible Cell-Loaded Ultrathin Ribbons for Minimally Invasive Delivery of Skeletal Muscle Cells

  • Salehi, S., Ostrovidov, Serge., Ebrahimi, M., Sadeghian, R., Liang, X., Nakajima, K., Bae, H., Fujie, T., Khademhosseini, A.
  • ACS Biomater. Sci. Eng, , DOI: 10.1021/acsbiomaterials.6b00696 (2017)

Sandwich fixation of electronic elements using free-standing elastomeric nanosheets for low-temperature device processes.

  • Okamoto, M., Kurotobi, M., Takeoka, S., Sugano, J., Iwase, E., Iwata, H., Fujie, T
  • J. Mater. Chem. C,, 5, 1321-1327 (2017)

Publication / 2016

  • Kumagai, H., Sawada, K., Takahashi, K., Sato, N., Takeoka, S., Fujie, T.
  • International Conference on Optical MEMS and Nanophotonics, 2016, 7565890(2016)

  • Ito, K., Saito, A., Fujie, T., Miyazaki, H.b, Kinoshita, M.c, Saitoh, D.b, , Ohtsubo, S., Takeoka, S.
  • Journal of Biomedical Materials Research - Part B Applied Biomaterials, 104(3), 585-593(2016)

  • Asao, K., Ogino, M., Iwano, A., Okamura, Y., Takeoka, S., Nagase, Y.
  • Kobunshi Ronbunshu, 73(1), 76-86(2016)

  • 木下 学, 檜 顕成, 藤枝 俊宣, 武岡 真司
  • 技術情報協会, 第1章第2節(2016)

  • Ferdinandus, Satoshi Arai, Shinji Takeoka, Shin’ichi Ishiwata, Madoka Suzuk, and Hirotaka Sato
  • ACS Sensors, 1 (10), 1222–1227(2016).

Optomechanical characterization of freestanding stretchable nanosheet based on polystyrene-polybutadiene-polystyrene copolymer

  • Kumagai, H., Sato, N., Takeoka, S., Sawada, K., Fujie, T., Takahashi, H
  • Appl. Phys. Express., 10, DOI: 10.7567/APEX.10.011601, (2016)

Stretchable, adhesive and ultra-conformable elastomer thin films

  • N. Sato, A. Murata, T. Fujie, S. Takeoka
  •  Soft Matter, 12,  9202-9209, (2016)

Large-scale fabrication of porous polymer nanosheets for engineering hierarchical cellular organization

  • Shoichiro Suzuki, Keisuke Nishiwaki, Shinji Takeoka, Toshinori Fujie
  • Advanced Materials Technologies, 1, DOI:10.1002/admt.201600064, (2016)

Glue-Free Stacked Luminescent Nanosheets Enable High-Resolution Ratiometric Temperature Mapping in Living Small Animals

  • T. Miyagawa, T. Fujie, Ferdinandus, T. T. Vo Doan, H. Sato, S. Takeoka
  • ACS Applied Materials & Interfaces,  8 (49), 33377–33385, (2016)

Sheet shape-controlling method for hundreds-nanometer-thick polymer film.

  • Shimbo, S., Fujie, T., Iwase, E.
  • Jpn. J. Appl. Phys, 55, 06GP21, (2016)

Interfacial Effects on the Crystallization and Surface Properties of Poly(L-lactic acid) Ultrathin Films.

  • Udagawa, A., Fujie, T., Kawamoto, Y., Saito, A., Takeoka, S., Asahi, T
  • Polymer J., 48, 157-161, (2016)

Facilely-fabricated luminescent nanoparticle thermosensor for real-time microthermography in living animals

  • Ferdinandus, Arai, S., Takeoka, S., Ishiwata, S., Suzuki, M. and Sato, H.
  • ACS Sensors, 1(10) , 1222 - 1227, (2016)

Focal calcium monitoring with targeted nanosensors at the cytosolic side of endoplasmic reticulum

  • Hou, Y., Arai, S., Takei, Y., Murata, A., Takeoka, S. and Suzuki, M.
  • Sci. Technol. Adv. Mater., 17(1), 293 - 299, (2016)

Phospholipase Cβ1 induces membrane tubulation and is involved in caveolae formation

  • T.Inaba, T.Kishimoto, M.Muratea, T.Tajima, S.Sakaia, M.Abe, A. Makino, N.Tomishige, R.Ishitsuka, Y.Ikeda, S.Takeoka, and T.Kobayashi
  • PNAS, 113(28), 7834–7839, (2016)

Fibrinogen -Chain PeptideCoated Adenosine 5' DiphosphateEncapsulated Liposomes Rescue Mice From Lethal Blast Lung Injury via Adenosine Signaling

  • Hagisawa, K, Kinoshita, M, Miyawaki, H, Sato, S, Miyazaki, H, Takeoka, S, Suzuki, H, Iwaya, K, Seki, S, Shoji, S, Saitoh, D, Nishida, Y, Handa, M,
  • Crit.Care Med., , 44, e827–e837, (2016)

Massive Fabrication of Polymer Microdiscs by Phase Separation and Freestanding Process

  • H. Zhang, M. Fujii, Y. Okamura, L. Zhang, and S. Takeoka
  • ACS Appl. Mater. Interfaces, 8 (25), 16296–16302, (2016)

ホスホリルコリン基を有するポリイミドの合成と生体適合性ナノシートの作製

  • 浅尾 幸平, 荻野 真里, 岩野 篤, 岡村 陽介, 武岡 真司, 長瀬 裕
  • 高分子論文集, 73(1), 76-86 , (2016)

生体組織に調和する高分子ナノシートの医療・ヘルスケアへの展開

  • 藤枝 俊宣, 山岸 健人, 武岡 真司.
  • 化学工業,, 67(2) , 49-54, (2016)

Development of free-standing polymer nanosheets for advanced medical and healthcare applications

  • T. Fujie
  • Polymer Journal (Focus Review), in press, DOI:10.1038/pj.2016.38
  • リンク

Polylactic acid nanosheets in prevention of postoperative intestinal adhesion and their effects on bacterial propagation in an experimental model

  • A. Hinoki, A. Saito, M. Kinoshita, J. Yamamoto, D. Saitoh and S. Takeoka
  • British Journal of Surgery, 103(5) in press, DOI: 10.1002/bjs.10122

Publication / 2015

  • M.Hashimoto, K.Taguchi, S.Ogaki, H.Watanabe, M.Kinoshita, K.Nishikawa, S.Takeoka, Y.Ikeda, M.Handa, M.Otagiri, T.Maruyama
  • Journal of Pharmaceutical Sciences, 104, 3968-3976(2015)

  • S.Arai, Ferdinandus, S.Takeoka, S.Ishiwata, H.Sato, M.Suzuki
  • Analyst, 140, 7534-7539(2015)

  • 藤枝 俊宣,武岡 真司
  • CMC出版, 251-263(2015)

Sustainable antimicrobial effect of silver sulfadiazine-loaded nanosheets on infection in a mouse model of partial-thickness burn injury


Patchwork Coating of Fragmented Ultra-Thin Films and Their Biomedical Applications in Burn Therapy and Antithrombotic Coating

  • Yosuke Okamura, Yu Nagase and Shinji Takeoka
  • Materials 2015, 8(11), 7604-7614; doi:10.3390/ma8115404
  • Link

Roll to roll processing of ultraconformable conducting polymer nanosheets

  • A. Zucca, K. Yamagishi, T. Fujie, S. Takeoka, V. Mattoli and F. Greco
  • J. Mater. Chem. C, 2015,3, 6539-6548
  • Link

A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

  • Homma M., Takei Y., Murata A., Inoue T., Takeoka S.
  • Chemical Communications, DOI: 10.1039/C4CC10349A
  • Link

Establishment of a total liquid ventilation system using saline-based oxygen micro/nano-bubble dispersions in rats

  • Kenta Kakiuchi, Kenichi Matsuda, Norikazu Harii, Keitaro Sou, Junko Aoki, Shinji Takeoka
  • Journal of Artificial Organs,(2015) 10.1007/s10047-015-0835-z
  • Link

A Cu-free clickable fluorescent probe for intracellular targeting of small biomolecules

  • Kento Yamagishi, Kazuaki Sawaki, Atsushi Murata and Shinji Takeoka
  • Chem. Commun., 2015,51, 7879-7882
  • Link

Treatment with fibrinogen γ-chain peptide-coated, adenosine 5′-diphosphate-encapsulated liposomes as an infusible hemostatic agent against active liver bleeding in rabbits with acute thrombocytopenia

  • Kohsuke Hagisawa; Kahoko Nishikawa; Rempei Yanagawa; Manabu Kinoshita; Mami Doi; Hidenori Suzuki; Keiichi Iwaya; Daizoh Saitoh; Shuhji Seki; Shinji Takeoka; et al.
  • Transfusion. 2015;55(2):314-325.
  • Link

Effect of Repeated Injections of Adenosine Diphosphate-Encapsulated Liposomes Coated with a Fibrinogen γ-Chain Dodecapeptide Developed as a Synthetic Platelet Substitute on Accelerated Blood Clearance in a Healthy and an Anticancer Drug-Induced Thrombocytopenia Rat Model

  • Kazuaki Taguchi; Mai Hashimoto; Shigeru Ogaki; Hiroshi Watanabe; Shinji Takeoka; Yasuo Ikeda; Makoto Handa; Masaki Otagiri; Toru Maruyama
  • Journal of Pharmaceutical Sciences,  (2015) in press. DOI: 10.1002/jps.24418
  • Link

Publication / 2014

  • S.Ishihara, Y.Furuki, J.P.Hill, K.Ariga, S.Takeoka
  • Journal of Nanoscience and Nanotechnology, 14, 5130-5137(2014)

  • Ostrovidov, S., Shi, X., Zhang, L., Liang, X., Kim, S-B., Fujie, T., Ramalingam, M., Chen, M., Nakajima, K., Al-Hazmi, F., Bae, H.,
  • Biomaterials, 35, 6268-6277(2014)

  • 藤枝 俊宣
  • 化学と工業, 67(11), 996-997(2014)

  • 藤枝 俊宣
  • バイオマテリアル-生体材料-, 32(1), 35-38(2014)

  • 藤枝 俊宣
  • バイオサイエンスとインダストリー, 72(2), 127-129(2014)

  • 藤枝 俊宣
  • 機能材料, 34(1), 32-39(2014)

Nanobiotechnology (アレクサンダー・セイファリアン著) -Chapter 6: Development of Nanosheet Technology Toward Advanced Nanomedical Engineering

  • 藤枝俊宣,武岡真司
  • One Central Press, イギリス
  • Link

細胞外マトリックスを規範とする高分子ナノシートの創製と生体組織工学への応用

  • 藤枝 俊宣
  • 高分子論文集 71(9), 408-417 (2014)

Intracellular delivery of universal proteins using a lysine headgroup containing cationic liposomes: Deciphering the uptake mechanism

  • Satya Ranjan Sarker; Ryosuke Hokama; Shinji Takeoka
  • Molecular Pharmaceutics. 2014;11(1):164-174.
  • Link

Periosteum-mimetic structures made from freestanding microgrooved nanosheets.

  • Shi, X.*, Fujie, T.*, Saito, A., Takeoka, S., Hou, Y., Shu, Y., Chen, M.,Wu, H., Khademhosseini, A.
  • Adv. Mater. , 26, 3290-3296 (2014)
  • Link

Enhanced cellular uptake of maleimide-modified liposomes via thiol-mediated transport

  • Tianshu Li, Shinji Takeoka *
  • International Journal of Nanomedicine, 9, 2849-2861 (2014).
  • Link

A Nanoparticle-Based Ratiometric and Self-Calibrated Fluorescent Thermometer for Single Living Cells

  • Yoshiaki Takei, Satoshi Arai, Atsushi Murata, Masao Takabayashi, Kotaro Oyama, Shin’ichi Ishiwata, Shinji Takeoka, and Madoka Suzuki
  • ACS NANO 2014, 8 (1), pp 198–206
  • See this article

Publication / 2013

  • S. R. Sarker, Y. Aoshima, R. Hokama, T. Inoue, K. Sou, and S. Takeoka
  • Int. J. Nanomedicine, 8,1361-1375(2013)

  • Y. Takei, A. Murata, K. Yamagishi, S. Arai, H. Nakamura, T. Inoue, and S. Takeoka
  • Chem. Commun., 49,7313-7315(2013)

Cationic Amino Acid Based Lipids as Effective Non-viral Gene Delivery Vectors for Primary Cultured Neurons

  • Yumiko Aoshima, Ryosuke Hokama, Keitaro Sou, Satya Ranjan Sarker, Kabuto Iida, Hideki Nakamura, Takafumi Inoue, and Shinji Takeoka
  • ACS Chem. Neurosci., 4, 514–1519 (2013).
  • See this article

Pharmacokinetic Study of Adenosine Diphosphate-Encapsulated Liposomes Coated with Fibrinogen γ-Chain Dodecapeptide as a Synthetic Platelet Substitute in an Anticancer Drug-Induced Thrombocytopenia Rat Model.

  • Taguchi K, Ujihira H, Watanabe H, Fujiyama A, Doi M, Takeoka S, Ikeda Y, Handa M, Otagiri M, Maruyama T.
  • J.Pharm. Sci.,102,3852–3859 (2013).
  • See this article

Development of Latanoprost-Loaded Biodegradable Nanosheet as a New Drug Delivery System for Glaucoma

  • Kenji Kashiwagi, Keisuke Ito, Hiroki Haniuda, Shinya Ohtsubo, and Shinji Takeoka
  • Invest. Ophthalmol. Vis. Sci., 54, 5629-5637 (2013).
  • See this article

A novel application of maleimide for advanced drug delivery: In vitro and in vivo evaluation of maleimide-modified pH-sensitive liposomes

  • Tianshu Li, Shinji Takeoka
  • Int.J.Nanomed., 8, 3855-3866 (2013).
  • See this article

Pharmacokinetic Study of the Structural Components of Adenosine Diphosphate-encapsulated Liposomes Coated with Fibrinogen γ-Chain Dodecapeptide as a Synthetic Platelet Substitute

  • Kazuaki Taguchi, Hayato Ujihira, Shigeru Ogaki, Hiroshi Watanabe, Atsushi Fujiyama, Mami Doi, Yosuke Okamura, Shinji Takeoka, Yasuo Ikeda, Makoto Handa, Masaki Otagiri, and Toru Maruyama
  • Drug Metabolism & Disposition, June 2013, 41 (6) doi: 10.1124/dmd.112.050005
  • See this article

Effective control of massive venous bleeding by "multi-overlapping therapy" using polysaccharide nanosheets in a rabbit inferior vena cava injury model

  • Kohsuke Hagisawa, Akihiro Saito, Manabu Kinoshita, Toshinori Fujie, Naoki Otani, Satoshi Shono, Young-Kwang Park, and Shinji Takeoka
  • J.Vasc.Surg.: Venous and Lymphatic Disorders, 1, 289-297 (2013).
  • See this article

Tapping-mode AFM study of tip-induced polymer deformation under geometrical confinement

  • Hong Zhang; Yukio Honda; Shinji Takeoka
  • Langmuir, 29,1333-1339 (2013).
  • See this article

Application of poly-l-lactic acid nanosheet as a material for wound dressing

  • Shimpo Aoki; Manabu Kinoshita; Hiromi Miyazaki; Akihiro Saito; Toshinori Fujie; Keiichi Iwaya; Shinji Takeoka; Daizoh Saitoh
  • Plastic and Reconstructive Surgery. 131, 236-240 (2013).
  • See this article

Novel therapeutic use of polysaccharide nanosheets for arachnoid plasty and enhancement of venous tensile strength in rat microneurosurgery

  • Naoki Otani; Manabu Kinoshita; Toshinori Fujie; Akihiro Saito; Shinji Takeoka; Daizoh Saitoh; Kohsuke Hagisawa; Hiroshi Nawashiro; Katsuji Shima
  • J.Clinical Neurosci., 20,301-305 (2013).
  • See this article

Fragmentation of Poly(lactic acid) nanosheets and patchwork treatment for burn wounds

  • Yosuke Okamura; Koki Kabata; Manabu Kinoshita; Hiromi Miyazaki; Akihiro Saito; Toshinori Fujie; Shinya Ohtsubo; Daizoh Saitoh; Shinji Takeoka
  • Advanced Materials,25,545-551 (2013).
  • See this article

Selective molecular permeability induced by glass transition dynamics of semicrystalline polymer ultrathin films

  • Toshinori Fujie; Yuko Kawamoto; Hiroki Haniuda; Akihiro Saito; Koki Kabata; Yukio Honda; Eriko Ohmori; Toru Asahi; Shinji Takeoka
  • Macromolecules, 46,395-402 (2013).
  • See this article

Drift and fluctuating motion of artificial platelets during the lateral transport and adhesion process near the wall

  • Hiroaki Tobimatsu; Antoine Paragon; Yosuke Okamura; Shinji Takeoka; Ryo Sudo; Yasuo Ikeda; Kazuo Tanishita
  • J.Biorheology, 26,11-20 (2013).
  • See this article

Intracellular click reaction with a fluorescent chemical Ca2+ indicator to prolong its cytosolic retention

  • Yoshiaki Takei , Atsushi Murata , Kento Yamagishi , Satoshi Arai , Hideki Nakamura , Takafumi Inoue and Shinji Takeoka
  • Chem. Commun., 49, 7313-7315 (2013).
  • See this article

Application of nanosheets as an anti-adhesion barrier in partial hepatectomy

  • Daisuke Niwa, Masatsugu Koide, Toshinori Fujie, Nobuhito Goda, Shinji Takeoka*
  • J.Biomed.Mater.Res. B: Applied Biomaterials, 101,1251–1258 (2013).
  • See this article

Publication / 2012

  • S. R. Sarker, S. Arai, M. Murate, H. Takahashi, M. Takata, T. Kobayashi, S. Takeoka
  • International Journal of Pharmaceutics, 422(1-2),364-373(2012)

  • 武岡 真司, 藤枝 俊宣
  • Material Stage, 12(7), 16-19(2012)

  • 藤枝 俊宣, 武岡 真司
  • NTS, 267-272(2012)

生体投与可能なナノ構造体の構築と血小板代替物への応用

  • 岡村陽介、武岡真司
  • 人工血液 20 (2), 38-47(2012)

高分子系ナノシートの外科手術用創傷被覆材、癒着防止剤としての可能性

  • 武岡 真司、藤枝 俊宣
  • MATERIAL STAGE, 12(7), 16-19(2012)

Ability of fibrinogen γ-derived dodecapeptides with different sequences to bind to rat platelets

  • Koji Tokutomi,Toshiaki Tagawa,Maki Korenaga,Masatoshi Chiba,Tomohiro Asai,Naohide Watanabe,Shinji Takeoka,Makoto Handa,Yasuo Ikeda,Naoto Okud
  • Int.J.Pharmaceutics, 438(1-2), 296 - 301 (2012)
  • See this article

Coordinative Nanoporous Polymers Synthesized with Hydrogen-Bonded Columnar Liquid Crystals

  • Shinsuke Ishihara,* Yusuke Furuki, Jonathan P. Hill, Katsuhiko Ariga, and Shinji Takeoka*
  • J. Nanosci. Nanotechnol., 12(10), 7885-7895 (2012)
  • See this article

Mass Spectrometric Screening of Ligand with Lower Off-rate from a Clikced-based Pooled Library

  • Arai, S.; Hirosawa, S.; Oguchi, Y.; Suzuki, M.; Murata, A.; Ishiwata, S.; Takeoka, S.
  • ACS Comb.Sci., 14, 451-455(2012)
  • See this article

Fibrinogen γ-chain peptide-coated, adenosine diphosphate-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage

  • Nishikawa K, Hagisawa K, Kinoshita M, Shono S, Katsuno S, Doi M, Yanagawa R, Suzuki H, Iwaya K, Saitoh D, Sakamoto T, Seki S, Takeoka S, Handa M.
  • J. Thromb. Haemostasis, 10(10), 2137-2148(2012)
  • See this article

Therapeutic efficacy of an antibiotic-loaded nanosheet in a murine burn-wound infection model

  • A.Saito, H. Miyazaki, T. Fujie, M. Kinoshita, S. Ohtsubo, D. Saitoh, S. Takeoka
  • Acta Biomaterialia, 2012, 8, 2932-2940
  • See this article

Morphological evolution within spin-cast ultrathin polymer blend films clarified by a freestanding method

  • Hong Zhang; Shinji Takeoka
  • Macromolecules, 2012, 45(10), 4315-4321
  • See this article

A TEMPO-Conjugated Fluorescent Probe for Monitoring Mitochondrial Redox Reactions.

  • S. Hirosawa, S. Arai, S. Takeoka
  • Chemical communications, 48, 4845-4847(2012)
  • See this article

Walking nanothermometers: Spatiotemporal temperature measurement of transported acidic organelles in single living cells.

  • Kotaro Oyama, Masao Takabayashi, Yoshiaki Takei, Satoshi Arai, Shinji Takeoka, Sinichi Ishiwata, Madoka Suzuki
  • Lab on a chip, 12, 1591-1593(2012)
  • See this article

An ultra-thin poly(L-lactic acid) nanosheet as a burn-wound dressing for protection against bacterial infection.

  • Hiromi Miyazaki, Manabu Kinoshita, Akihiro Saito, Toshinori Fujie, Koki Kabata, Etsuko Hara, Satoshi Ono, Shinji Takeoka, Daizoh Saitoh
  • Wound Repair and Regeneration, 2012;20(4):573-579
  • See this article

Publication / 2011

  • Fujie, T., Okamura, Y., Takeoka, S.
  • Functional Polymer Films , 2, 907-931(2011)

  • Sakai, H., Takeoka, S., Kobayashi, K.
  • Current Pharmaceutical Design , 17(22), 2352-2359(2011)

  • Sakai, H., Miyagawa, N., Horinouchi, H., Takeoka, S., Takaori, M., Tsuchida, E., Kobayashi, K.
  • Polymers for Advanced Technologies , 22(8), 1216-1222(2011)

Aqueous colloidal mesoporous nanoparticles with ethenylene-bridged silsesquioxane frameworks.

  • Urata, C.; Yamada, H.; Wakabayashi, R.; Aoyama, Y.; Hirosawa, S.; Arai, S.; Takeoka, S.; Yamauchi, Y.; Kuroda, K.
  • J. Am. Chem. Soc., 133(21), 8102-8105(2011)
  • See this article

Fluorescent “Turn-on” system utilizing a quencher-conjugated peptide for specific protein labeling of living cells

  • Satoshi Arai, Su-In Yoon, Atsushi Murata, Masao Takabayashi, Xiaoyu Wu, Yixin Lu, Shinji Takeoka, Miwako Ozaki
  • Biochem. Biophys. Res. Commun., 1, 211-216(2011)
  • See this article

Chirality Sensing by Nonchiral Porphines

  • Jan Labuta, Shinsuke Ishihara, Atsuomi Shundo, Satoshi Arai Shinji Takeoka, Katsuhiko Ariga, Jonathan P. Hill
  • Chemistry - A European Journal, 17(13), 3558-3561(2011)
  • See this article

Increased viscosity of hemoglobin-based oxygen carriers retards no-binding when perfused through narrow gas-permeable tubes

  • Hiromi Sakai, Naoto Okuda, Shinji Takeoka, and Eishun Tsuchida
  • Microvascular Research, 81(2), 169-176(2011)
  • See this article

Free-Standing Poly(l-lactic acid) Nanofilms Loaded with Superparamagnetic Nanoparticles

  • Taccola S, Desii A, Pensabene V, Fujie T, Saito A, Takeoka S, Dario P, Menciassi A, Mattoli V
  • Langmuir, 27(9), 5589-5595 (2011)
  • See this article

Convenient method for surface modification by patching a freestanding anti-biofouling nanosheet

  • Toshinori Fujie , Hiroki Haniuda and Shinji Takeoka
  • J. Mater. Chem., 21, 9112-9120(2011)
  • See this article

A few immobilized thrombins are sufficient for platelet spreading

  • Okamura Y, Schmidt R, Raschke I, Hintze M, Takeoka S, Egner A, Lang T
  • Biophysical Journal, 100(8), 1855-1863(2011)
  • See this article

Decoration of fibrinogen γ-chain peptide on adenosine diphosphate-encapsulated liposomes enhances binding of the liposomes to activated platelets

  • Koji Tokutomi, Toshiaki Tagawa, Maki Korenaga, Masatoshi Chiba, Tomohiro Asai, Naohide Watanabe, Shinji Takeoka, Makoto Handa, Yasuo Ikeda, Naoto Oku
  • International Journal of Pharmaceutics, 407(1-2), 151-157(2011)
  • See this article

Heterofunctional nanosheet controlling cell adheasion properties by collagen coating

  • Niwa, D., Fujie, T., Lang, T., Goda, N., Takeoka, S.
  • J. Biomaterials Applications, 27(2), 131-141(2011)
  • See this article

Novel technique of overlaying a poly-l-lactic acid nanosheet for adhesion prophylaxis and fixation of intraperitoneal onlay polypropylene mesh in a rabbit model

  • Keiichi. Fujino, Manabu. Kinoshita, Akihiro. Saitoh, Hidekazu. Yano, Kahoko. Nishikawa, Toshinori. Fujie, Keiichi. Iwaya, Minoru Kakihara, Shinji. Takeoka and Daizoh. Saitoh, Yuji. Tanaka
  • Surg. Endosc., 25(10), 3428-3436(2011)
  • See this article

Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)

  • T.Nabetani, A.Makino, F.H. Matsuda,T. Hirakawa, S. Takeoka, N. Okino, M. Ito, T. Kobayashi, Y. Hirabayashi
  • J. Lipid Research, 52, 1294-1302(2011)
  • See this article

Ultrastructural analysis of thrombin-induced interaction between human platelets and liposomes carrying fibrinogen γ-chain dodecapeptide as a synthetic platelet substitute

  • Hidenori Suzuki, Yosuke Okamura, Yasuo Ikeda, Shinji Takeoka, Makoto Handa
  • Thrombosis Research, 128(6), 552-559(2011)
  • See this article

Ultra-thin conductive free-standing PEDOT/PSS nanofilms

  • Francesco Greco, Alessandra Zucca, Silvia Taccola, Arianna Menciassi, Toshinori Fujie, Hiroki Haniuda, Shinji Takeoka, Paolo Dario, and Virgilio Mattoli
  • Soft Matter, 7, 10642-10650(2011)
  • See this article

Functional Polymer Films, Chapt 29 Fabrication, Properties, and Biomedical Applications of Nanosheets

  • Toshinori Fujie, Yosuke Okamura, Shinji Takeoka
  • WILEY-VCH(2011)

Publication / 2010

  • Obata, Y., Tajima, S., Takeoka, S.
  • Journal of Controlled Release, 142(2), 267-276(2010)

  • Sakai, H., Okuda, N., Sato, A., Yamaue, T., Takeoka, S., Tsuchida, E.
  • American Journal of Physiology - Heart and Circulatory Physiology, 298(3), H956-H965(2010)

  • Tobimatsu, H., Paragon, A., Okamura, Y., Takeoka, S., Sudo, R., Tanishita, K.
  • IFMBE Proceedings, 31 IFMBE, 1075-1078(2010)

  • 藤枝 俊宣, 齋藤 晃広, 武岡 真司
  • 表面, 48(7), 211-219(2010)

  • 木下 学, 藤枝 俊宣
  • 化学と教育, 58, 570-573(2010)

Release abilities of adenosine diphosphate from phospholipid vesicles with different membrane flexibilities properties and their hemostatic effects as a platelet substitute.

  • Okamura, Y., Katsuno, S., Suzuki H., Maruyama, H., Handa, M., Ikeda, Y., Takeoka, S.
  • S.Journal of Controlled Release(2010)

Construction of a "turn-on" fluorescent probe system for His-tagged proteins.

  • Murata, A., Arai, S., Su-In, Y., Takabayashi, M., Ozaki, M., Takeoka, S.
  • Bioorganic & Medicinal Chemistry Letters(2010)

高分子超薄膜(ナ ノシート)の医用材料としての展開

  • 藤枝 俊宣, 武岡 真司
  • 高分子, 59 (12), 2010

Adhesion and proliferation of skeletal muscle cells on single layer poly(lactic acid) ultra-thin films.

  • Ricotti, L., Taccola, S., Pensabene, V., Mattoli, V., Fujie, T., Takeoka, S., Menciassi, A., Dario, P.
  • Biomed Microdevices, 12, 809-819 (2010)

Synthesis and Self-Assembling Behavior of a Porphyrin Bearing Multiple meso- Conjugated Barbiturates.

  • Arai, S., Okamura, T., Takeoka, S.
  • Tetrahedron Letters,51 (39)/,5177-5180

A Nano-Fibrous Assembly of Collagen / Hyaluronic Acid for Controlling Cell- Adhesive Properties.

  • T. Fujie, S. Furutate, D. Niwa, S. Takeoka
  • Soft Matter, 6, 4672-4676 (2010)

Dual therapeutic action of antibiotic-loaded nanosheets for the treatment of gastrointestinal tissue defects.

  • T. Fujie, A. Saito, K. Kinoshita, H. Miyazaki, S. Ohtsubo, D. Saitoh, S. Takeoka
  • Biomaterials, 31, 6269 -6278(2010)

Sealing effect of a polysaccharide nanosheet for murine cecal puncture.

  • Fujie, T., Kinosita, M., Shono, S., Saito, A., Okamura, Y., Saitoh, D., Takeoka, S.
  • Surgery, 148, 48-58 (2010)

「~体内組織に 『癒着しない』~ナノシートからなる手術用フィルムの開発」

  • 藤枝 俊宣, 松谷 哲行, 木下 学, 武岡 真司
  • Material Stage, 10(4), 4-6 (2010)

「穿孔性腹膜炎 に対するナノシートの応用」

  • 藤枝 俊宣, 木下 学, 齋藤 大蔵, 武岡 真司
  • Surgery Frontier,17(2), 37-43 (2010)

肺瘻修復におけ る超薄膜状ナノバイオマテリアルの臨床応用へ向けた基礎的検討

  • 松谷哲 行、藤枝俊宣、木下学、尾関雄一、武岡真司
  • 日本 呼吸器外科会雑誌(JACSURG), 1, 2-7 (2010)

Evaluation of cationic liposomes composed of an amino acid-based lipid for neuronal transfection.

  • Y. Obata, G. Ciofani, S. Raffa, A. Cuschieri, A. Menciassi, P. Dario, S. Takeoka
  • Nanomedicine: Nanotechnology, Biology, and Medicine, 6, 70-77 (2010)

Visualization of Liposomes Carrying Fibrinogen γ-Chain Dodecapeptide Accumulated to Sites of Vascular Injury Using Computed Tomography

  • Y. Okamura, K. Eto, H. Maruyama, M. Handa, Y. Ikeda, S. Takeoka
  • Nanomedicine: Nanotechnology, Biology, and Medicine, 6(2), 391-396 (2010)

Publication / more