NEWS

2019/7/29

Summer seminar 2019 (7/27-29) was held in Karuizawa seminar house.

2019/7/2

Taknori Nakanishi, Kento Yamagishi, Shinji Takeoka, Toshinori Fujie was published in Applied Physics Express.
"Sinter-free stretchable conductive inks composed of polystyrene-block-polybutadiene-block-polystyrene and silver flakes in tetrahydrofuran"
Takenori Nakanishi, Kento Yamagishi, Shinji Takeoka, Toshinori Fujie

2019/5/17

An original article written by Jieyan He, Tianshu Li, Tomasz Próchnicki,Gabor Horvath,Eicke Latz ,and Shinji Takeoka was published in Biochem Biophys Rep
"Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency"
Jieyan He, Tianshu Li, Tomasz Próchnicki,Gabor Horvath,Eicke Latz ,and Shinji Takeoka

2019/5/17

Kon Son and Meiting Hao will present recent works in the 68th Society of Polymer Science, Japan Annual Meeting (5/29-31, 2019, Osaka, Japan) .
1M12 "Fission of rod-shaped vesicle by rearrangement of component amphiphilic polypeptides" (Kon Son)
2Pe049 "Directed self-deployment of the thin film emission device by selective coating of fluoropolymer" (Meiting Hao)

2019/5/17

An original article written by Li T, Zehner M, He J, Próchnicki T, Horvath G, Latz E, Burgdorf S, Takeoka S was published in International Journal of Nanomedicine
"NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells"
Li T, Zehner M, He J, Próchnicki T, Horvath G, Latz E, Burgdorf S, Takeoka S

2019/5/17

Arihiro Hasebe, Yoshitaka Suematsu, Shinji Takeoka, Toshinori Fujie was published in ACS Biomaterials Science & Engineering.
"Biohybrid Actuators Based on Skeletal Muscle-Powered Microgrooved Ultrathin Films Consisting of Poly(styrene-blockbutadiene-block-styrene)"
Arihiro Hasebe, Yoshitaka Suematsu, Shinji Takeoka, Tommaso Mazzocchi, Lorenzo Vannozzi, Leonardo Ricotti, Toshinori Fujie

2019/2/14

Kenta Kakiuchi presented recent works in Academic meeting of the Inamon Medical Association(2/2-3, 2019, Tokyo), and received The Excellent Aword.
Oral presentation(session 1)Establishment of Total Liquid Ventilation System using Oxygen Micro/Nano Bubble Dispersion

Message from Prof. TAKEOKA


Welcome to Takeoka Laboratory. Our Lab studies biomolecular assembling sciences for nano-medicine. Molecular assembling and cooperative phenomena of biomolecules and/or biomacromolecules give us useful implications to construct smart nanodevices having multi-functions for biomedical application (Nano-medicine). Our research group quests the molecular assembling science and engineering of amphiphilic molecules such as phospholipids, glycolipids, aminolipids, and polyethyleneglycol (PEG)-lipids interacted with biomacromoleucles such as bioactive compounds, genes or proteins, in order to design and construct the nanocarriers in biomedical applications such as controlled drug delivery and release systems.


Research Topics

Nanosheet Group

Development of a free-standing ultra-thin and biocompatible polymer nanosheets

Imaging Group

To reveal a lot of unknown cellular activities, we are constructing novel fluorescent probes for bio-imaging

Liposome Group

Liposome should be multi-functional platform for drug delivery system

Platelet Group

Liposome based artificial platelets could promote platelet aggregation