An original article written by Dr. Toshinori Fujie (Assistant Professor), Shoichiro Suzuki (alumni) and Keisuke Nishiwaki was published from Advanced Materials Technologies.
Large-sale fabrication of porous polymer nanosheets for engineering hierarchical cellular organization
S. Suzuki, K. Nishiwaki, S. Takeoka, T. Fujie, Advanced Materials
Technologies, in press, DOI:10.1002/admt.201600064 / Link


Assistant Prof. Toshinori Fujie, Masato Takikawa, and Keisuke Nishiwaki presented recent works in 10th World Biomaterials Congress (05/17-22/2016, Montreal, Canada, WBC). And Masato Takikawa has been granted "the WBC 2016 – McGill University Merit Trainee Award" (WBC awards).
"title", (Presenter)
"Roll-to-roll fabrication of conductive polymer nanosheets for the development of ultraconformable skin-contact electrodes", (Dr. Toshinori Fujie)
"Transfusion with synthetic platelet substitutes, H12-(ADP) liposomes, effectively rescues thrombocytopenic rabbits from massive hemorrhage", (Masato Takikawa)
"Formulation design of polymer nanosheets for controlled drug release", (Keisuke Nishiwaki)


Dr. Toshinori Fujie's work (Assistant Professor, Waseda Institute for Advanced Study) was highlighted on a cover art in the July 2016 issue of Polymer Journal (Nature Publishing Group).
Development of free-standing polymer nanosheets for advanced medical and healthcare applications T. Fujie, Polymer Journal (Focus Review), Polymer Journal, 48(7), 773-780 (2016). DOI:10.1038/pj.2016.38

This Focus Review summarizes the recent development of nanosheet technology for biomedical application.
Cover image was inspired by the night-time sky of July in Japan.
Title: "Summer Triangle" in Your Hand: an ultra-conformable conductive nanosheet bridging LEDs on the skin.
This image was designed by Kento Yamagishi, Marin Okamoto, and Daichi Someya.
Collaborator: Dr. Francesco Greco and Dr. Virgilio Mattoli (Italian Institute of Technology)
Article / Cover art

(Reprinted Courtesy of Nature Publishing Group)


A review article written by Dr. Toshinori Fujie (Assistant Professor) was published from Polymer Journal as a Focus Review paper.
Development of free-standing polymer nanosheets for advanced medical and healthcare applications
T. Fujie, Polymer Journal (Focus Review), in press, DOI:10.1038/pj.2016.38


Dr. Francesco Greco and Ms. Agostina Grillone (Fellow-PhD) from Istituto Italiano di Technologia (IIT) are staying at Takeoka laboratory for 4 months (February - May) and 6 months (February - July), respectively, to conduct collaborative research.


Dr. Shinji Takeoka, Dr. Francesco Greco, Kento Yamagishi, and Keisuke Nishiwaki will present recent works in "Nanotechnology Forum at Waseda University" (03/14/2016 Mon. 14:30-19:30).

Message from Prof. TAKEOKA

Welcome to Takeoka Laboratory. Our Lab studies biomolecular assembling sciences for nano-medicine. Molecular assembling and cooperative phenomena of biomolecules and/or biomacromolecules give us useful implications to construct smart nanodevices having multi-functions for biomedical application (Nano-medicine). Our research group quests the molecular assembling science and engineering of amphiphilic molecules such as phospholipids, glycolipids, aminolipids, and polyethyleneglycol (PEG)-lipids interacted with biomacromoleucles such as bioactive compounds, genes or proteins, in order to design and construct the nanocarriers in biomedical applications such as controlled drug delivery and release systems.

Research Topics

Nanosheet Group

Development of a free-standing ultra-thin and biocompatible polymer nanosheets

Imaging Group

To reveal a lot of unknown cellular activities, we are constructing novel fluorescent probes for bio-imaging

Liposome Group

Liposome should be multi-functional platform for drug delivery system

Platelet Group

Liposome based artificial platelets could promote platelet aggregation